The success of treatment outcomes, especially in children and adolescents, depends on a number of factors; from the etiology of the disease itself, the influence of the environment, the approach to understanding the needs of the child in relation to the stage of development and mental functioning. In this process, apart from the disease process itself, the relationship between parents and health care staff, the way of establishing a relationship, ie communication, plays an important role. In working with sick children, especially those who were involved in many forms of medical interventions due to the type of disease, we gained insight into the dissatisfaction of children, parents and health professionals regarding organizational and professional needs, which reflects on the treatment process and requires additional education and help.